ADR Case Reports from 2006～2007 in Our Hospital:A Retrospective Analysis / 中国药房

ABSTRACT

OBJECTIVE: To investigate the characteristics and regularity of adverse drug reactions(ADR) occurred in our hospital for reference of clinical rational drug use.METHODS: 1 183 ADR cases reported in our hospital between 2006 and 2007 were analyzed statistically using Excel in respect of patients' sex,age,routes of administration,variety of drugs and clinical manifestations etc.RESULTS: Of the 1 183 ADR cases,268(22.65%) were submitted by clinical departments,462(39.05%) by the department of pharmacy,and 441(37.28%) by central injection room.ADR incidence rate was slightly lower in males than in females.Patients over the age of 31 years showed a higher incidence of ADR.901 cases(76.16%) were induced by intravenous route.662 were induced by anti-infectives,followed by the traditional Chinese medicine(163 cases) and cardiovascular system drugs(149 cases).The most common manifestation of ADR was lesion of digestive system(301 cases),followed by lesions of skin and its appendages(236 cases) and damage of central nervous system(224 cases).CONCLUSION: Great importance should be attached to ADR monitoring as well as the analysis and evaluation of ADR so as to ensure safe and effective medication.