Effects of SDZ on LOVO Cell Line and the Expression of E-Cadherin and N-Cadherin / 中国药房
China Pharmacy
; (12)2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-531610
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To investigate the effects of SDZ on LOVO cell line and the expression of E-Cadherin and N-Cadherin.METHODS:
The apoptosis of SDZ on growth of LOVO cells was observed under electron microscope and inverted microscope. The expression of E-Cadherin and N-Cadherin treated by SDZ were detected by RT-PCR.RESULTS:
SDZ promoted the apoptosis of LOVO cell lines and increased the expression of E-Cadherin,however,it did no effect on the expression of N-Cadherin.CONCLUSION:
SDZ can enhance the intercellular adhesiveness and degrade the capability of infiltration and metastasis of tumor cells.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Document type:
Article