Expression of p27~(Kip1) and cyclin D1 in human gastric carcinoma and its prognostic significance / 中国癌症杂志
China Oncology
; (12)1998.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-536076
Responsible library:
WPRO
ABSTRACT
Purpose:
This study was designed to investigate the expression of p27 Kip1 and cyclin D1 in gastric carcinoma in relation to biological behavior and prognosis.Methods:
p27 Kip1 and cyclin D1 expression at protein level were determined by immunohistochemistry technique in 92 patients with gastric carcinoma.Results:
Of the 92 patients, p27 Kip1 expression was low in 28(71.8%) and high in 11(12%),respectively. Cyclin D1 expression was low in 32 (72.7%) and high in 12 (13%) ,respectively.p27 Kip1 expression level was correlated with histological grade, depth of invasion, lymph-node metastasis, TNM stage( P
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Oncology
Year:
1998
Document type:
Article