Curcumin inhibits leukemia cell line HL_60 /ADR / 中国免疫学杂志
Chinese Journal of Immunology
; (12)1985.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-536888
Responsible library:
WPRO
ABSTRACT
Abstract Objective:
To explore the suppression of curcumin on leukemia cell line HL60/DAR.Methods:
The suppression of curcumin onleukemia cell line HL60/DAR was studied by MTT;the apoptosis was studied by flow cytometric Annexin V/PI dual labeling technique and fluo-rescence microscope;the change in apoptosis related gene bcl-2 was studied by flow cytometry.Results:
CUrcumin suppressed the growth ofHL60/DAR obviously IC50 were 8.94,5.2l,3.82 ?g/ml for 24,48,72 h respectively. Curcumin induced Hl60/DAR cells to apoptosisdeath. CUrcumin suppressed the expression of bcl-2.Conclusion:
Curcumin can suppress the growth of HL60/DAR cells.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
1985
Document type:
Article