Long-term results of endocrinotherapy and(or) radiotherapy for moderately and far advanced prostate cancer / 中华泌尿外科杂志

ABSTRACT

Objective To study the longterm result of endocrinotherapy and (or) radiotherapy for moderately and far advanced prostate cancer. Methods 256 cases of moderately or far advanced prostate cancer were treated with endocrinotherapy (surgical castration + postoperative drug administration) and (or) radiotherapy.182 cases were of stage C and 74 stage D.There were 236 adenocarcinoma,7 squamous cancer and 13 undifferentiated cancer.Gleason score was ≥6 in 202 patients and 134 had pelvic lymphoid metastasis. Results In 92.2%of the patients,the serum PSA dropped under 2 ng/ml shortly after the treatment.The overall 5,10,15 year survival rates were 48.8%,29.7% and 13.3% respectively.For stage C cases,these were 58.2%,38.4%,17.7% and for stage D 25.7%,6.4%,0.The 5 and 10 year survival rates were significantly different between stage C and D(P