A Case of Hyalinizing Spitz Nevus: A Rare Variant in the Spectrum of Spitz Nevus / 대한피부과학회지
Korean Journal of Dermatology
; : 195-197, 2017.
Article
in Ko
| WPRIM
| ID: wpr-53858
Responsible library:
WPRO
ABSTRACT
Hyalinizing Spitz nevus was first introduced in 1994 by Suster. It is considered a rare variant in the spectrum of Spitz nevus, with only a dozen cases having been reported to date. Herein we report a case of a 28-year-old Korean woman who had a brown papular lesion on the left palm, which was diagnosed as hyalinizing Spitz nevus. Upon histopathological investigation, discohesive growth patterns of nevus cells in a hyalinized stroma were noted. Immunohistochemical stains showed positive reactivity of nevus cells with S-100 protein and vimentin, but negative stains with HMB-45 and CD68. This case demonstrates a rare variant of Spitz nevus located on an unusual site, and calls for awareness in the diagnosis of cutaneous lesions that histologically exhibit a prominent hyalinized stroma.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Vimentin
/
Biopsy
/
S100 Proteins
/
Nevus, Epithelioid and Spindle Cell
/
Diagnosis
/
Diagnosis, Differential
/
Coloring Agents
/
Hyalin
/
Nevus
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
Ko
Journal:
Korean Journal of Dermatology
Year:
2017
Document type:
Article