Expression of KAI1 protein and its clinicopathological significance in breast cancer / 中国癌症杂志
China Oncology
; (12)2001.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-539465
Responsible library:
WPRO
ABSTRACT
Purpose:
To investigate the expression of KAI1 protein and its clinicopathological significance in breast cancer.Methods:
Immunohistochemical staining ( S-P method) was used to detect the expression of KAI1 protein in specimens from 107 breast cancer and 30 adjacent normal breast tissues.Results:
KAI1 protein positive rate in breast cancer tissues is significantly lower than that of adjacent nomal breast( P 0. 05).Conclusions:
These data suggest that in advanced breast cancer, KAI1 is down-regulated and decrease in KAI1 ecpression plays an important role in the malignant progression of breast cancer. Therefore, detection of KAI1 protein might be a potentially valuable indicator for staging human breast cancer and predicting prognosis.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Oncology
Year:
2001
Document type:
Article