Cytokine influence on thyrocytes apoptosis and related protein expression in patients with Graves' disease / 中国免疫学杂志
Chinese Journal of Immunology
; (12)2001.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-541900
Responsible library:
WPRO
ABSTRACT
Objective:
To investigate cytokine(TNF-?,IL-1) effect on apoptosis and express of related protein in thyrocytes and the relationship with pathogenesis in Graves' disease(GD).Methods:
To test thyroid tissues from 50 patients with GD Fas expression by immunohistochemical method.Thyroid tissues were collected from samples of GD operation and were cultured by primary culture method.Content of sFas in culture medium was tested by ELISA.Fas/sFas mRNA were tested by RT-PCR.Cytokine inducing apoptosis in Graves' disease showes observation group,normal people showes control group.Results:
Compare apoptosis culture rate there is significant difference(P
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
2001
Document type:
Article