Effects of alpha-1-adrenergic receptor subtype-selective antagonists on lower urinary tract function in rats with bladder outlet obstruction / 中华泌尿外科杂志

ABSTRACT

500 mg,frequency was reduced in rats treated with tamsulosin (P500 mg,and the combined ?1a/?1dAR antagonist tamsulosin reduces urinary frequency more than the ?1aAR selective antagonist 5MU.This finding supports the hypothesis that the ?1dAR is important in mediating irritative symptoms.