Perioperative changes of the plasma NO and ET- 1 in the patients with portal hypertension after splenorenal shunt operation / 中国现代普通外科进展

ABSTRACT

Objective: To study the perioperative changes of the plasma NO and ET- 1 in the patients with the portal hypertension after splenorenal shunt operation. Me thod s The plasma NO and ET- 1 of the perioperative period was detected in the cirrhotic patients with portal hypertension after distal splenorenal shunt, NO was masuredusing the Griesss and ET- 1 by the radioim- munoassay. R e su lts Compared with control group and cirhosis group,plasma ET- 1 and NO levels significantly increased in portal hypertension group. Compared with preoperative levels, plasma NO and ET- 1 levels significantly decreased in the patients with portal hypertension after surgery ( P