Successful Xenograft of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimen from Human Extrahepatic Cholangiocarcinoma into an Immunodeficient Mouse
Gut and Liver
; : 805-808, 2015.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-55055
Responsible library:
WPRO
ABSTRACT
Patient-derived tumor xenograft is the transfer of primary human tumors directly into an immunodeficient mouse. Patient-derived tumor xenograft plays an important role in the development and evaluation of new chemotherapeutic agents. We succeeded in generating a patient-derived tumor xenograft of a biliary tumor obtained by endoscopic ultrasound-guided fine-needle aspiration from a patient who had an inoperable extrahepatic cholangiocarcinoma. This patient-derived tumor xenograft will be a promising tool for individualized cancer therapy and can be used in developing new chemotherapeutic agents for the treatment of biliary cancer in the future.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Transplantation, Heterologous
/
Bile Duct Neoplasms
/
Cholangiocarcinoma
/
Endoscopic Ultrasound-Guided Fine Needle Aspiration
/
Heterografts
/
Mice, Nude
Limits:
Animals
/
Humans
/
Male
Language:
English
Journal:
Gut and Liver
Year:
2015
Document type:
Article