EFFECT OF CLONIDINE ON CAT ARRHYTHMIAS OCCURRED DURING MYOCARDIAL ISCHEMIA / 中国药理学通报

ABSTRACT

Study was carried on pentobarbital anesthetized cats to investi-gate the effect of clonidine on arrhythmias induced by coronary occlusion. Clonidine 15???g/kg iv 15min prior to ligation of left anterior descending coronary artery significantly reduced the frequenecy of arrhythmias: the ventricular premature bats ( phase Ia, VPB from 80% in controls to 20%,P