A study on the labeling of melanocytic tumors and nevi with anti-human proliferative cell antibody Ki-67 / 第三军医大学学报
Journal of Third Military Medical University
; (24)1988.
Article
in Zh
| WPRIM
| ID: wpr-550937
Responsible library:
WPRO
ABSTRACT
Fifteen cases of malignant melanoma,17 cases of acquired nevus,18 cases of congenital small nevus,and 3 cases of congenital giant nevus were labeled with anti-human prolifera-tive cell antibody Ki-67 with ABC labeling method.It was found that 13 out of the 15 cases of malignant melanoma were positive and the positive rate of the tumor cells was ranged between 2% to 33%.After culture,the positive rate of the melanoma cells was 88%.But all the 3.types of melanocytic nevi were negative.The findings suggest that the labeling of anti-human proliferative cell antibody Ki-67 is a sensitive and specific method to identify melanocytic tumors and it is not sensitive enough to differentiate the minor changes of the 3 types of nevi.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Journal of Third Military Medical University
Year:
1988
Document type:
Article