Effect of early postoperative intraperitoneal chemotherapy versus that of intravenous chemotherapy on the immunity of patients with gastrointestinal carcinoma / 临床外科杂志

ABSTRACT

Objective TO compare the effect of early postoperative intraperitoneal chemotherapy (EPIC) with that of intravenous chemotherapy (IVC)on the immunity of patients with gastrointestinal carcinoma (GC).Methods 36 patients were divided into two groups each with 18 cases, one group received EPIC and the other IVC, then determined the serum T-lymphocyte subsets (T LS) and sIL-2R before and after the chemotherapy.Results Serum CD3, CD4 and sIL 2R in GC patients after the chemotherapy decreased more significantly than those of before the chemotherapy (P0.1),but mean sIL 2R level in EPIC group was lower than that in IVC (0.05