The influence of IFN on expression of chemokines IP-10,Mig in the patients with chronic hepatitis B / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
; (12)2001.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-560913
Responsible library:
WPRO
ABSTRACT
Objective To study the levels of some CXC chemokines mRNA in patients with chronic hepatitis B and its changes after combinative treatment of two types interferon-?(IFN-?)with Ribavirin.The logarithm rate of chemokine/GAPDH was regarded as the extreme level of chemokine.Methods The different levels of IP-10 and Mig mRNA in peripheral blood mononuclear cells(PBMC)of chronic hepatitis B were kinetically detected by real-time polymerase chain reaction(real-time PCR)in different treatment stages.Results The expression levels of IP-10 and Mig mRNA in peripheral blood of patients were(0.7387?0.0768),(0.6883?0.0693),respectively.Which were significantly higher than that in normal controls(P
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2001
Document type:
Article