Establishment of and Effects of BPV on Experimental Allergic Encephalomyelitis in Lewis Rats / 医学研究杂志
Journal of Medical Research
; (12)2006.
Article
in Zh
| WPRIM
| ID: wpr-563874
Responsible library:
WPRO
ABSTRACT
Objective To establish the animal model of experimental allergic encephalomyelitis(EAE)in Lewis rats.Methods The EAE was induced by giving hypodermal injections in feet with spinal cords homogenate of guinea pigs(GPSCH)and complete Freund's adjuvant(CFA)containing 8mg.ml-1 bacille calmette guerin(BCG).The EAE model was evaluated by clinical manifestations and pathologic findings which was studied with the aid of light and electron microscope.Results The EAE in Lewis rats had an incidence of 9/10,a latency of 12.6?1.01d.Bordetella pertussis vaccine(BPV)could increase the morbidity,shorten the latency(P
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Journal of Medical Research
Year:
2006
Document type:
Article