Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs
Journal of Veterinary Science
; : 123-126, 2016.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-56502
Responsible library:
WPRO
ABSTRACT
Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Adipose Tissue
/
Acute Disease
/
Treatment Outcome
/
Decompression, Surgical
/
Mesenchymal Stem Cell Transplantation
/
Dog Diseases
/
Intervertebral Disc Degeneration
/
Pain Perception
/
Intervertebral Disc Displacement
Limits:
Animals
Language:
English
Journal:
Journal of Veterinary Science
Year:
2016
Document type:
Article