Congenital Peribronchial Myofibroblastic Tumor: A Case Study and Literature Review
Korean Journal of Pathology
; : 172-176, 2013.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-56544
Responsible library:
WPRO
ABSTRACT
Congenital peribronchial myofibroblastic tumor (CPMT) is a benign pulmonary spindle cell neoplasm of intrauterine and perinatal period, which is thought to arise from primitive peribronchial mesenchyme. We present a case detected incidentally in a one-month-old infant. The solid and partially necrotic tumor involved the right middle and lower lobes of the lung with extension to the diaphragm. Histologically, the tumor was composed of fasciculated monotonous spindle cells, proliferating peribronchiolar cartilage and round cells with rich vasculature, and high mitotic activity was identified in the round cell area. Immunohistochemical and electron microscopic studies showed that the spindle cells were myofibroblastic in phenotype. Although the tumor showed several malignant pathological features, recurrence was not observed in the two-year follow-up period, consistent with the benign clinical behavior of CPMT.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Recurrence
/
Diaphragm
/
Cartilage
/
Follow-Up Studies
/
Electrons
/
Myofibroblasts
/
Lung
/
Mesoderm
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Infant
Language:
English
Journal:
Korean Journal of Pathology
Year:
2013
Document type:
Article