Chemical constituents of Dysosma pleiantha / 中草药

ABSTRACT

Objective To study the chemical constituents of Dysosma pleiantha.Methods Acidic resins were precipitated by 1% HCl solution, then the constituents were isolated and purified on repeated silica gel column.They were identified and structurally elucidated by physicochemical constants and spectral analysis.Results Ten compounds were obtained and identified podophyllotoxone (Ⅰ), dehydropodophyllotoxin (Ⅱ), podophyllotoxin (Ⅲ), 4′-demethylpodophyllotoxin (Ⅳ), 4′-demethyldehydropodophyllotoxin (Ⅴ), kaempferol (Ⅵ), quercetin (Ⅶ), n-hexadecanoic acid (Ⅷ), ?-sitosterol (Ⅸ), and daucosterol (Ⅹ).Conclusion Compound Ⅴ is a new compound, compounds Ⅷ-Ⅹ are first separated from the plants of Dysosma Woodson and other compounds are first separated from D.pleiantha.