Study of the relationship between morphological characteristics of tumor microvasculature and blood supply type of primary hepatocellular carcinoma observed under DSA / 介入放射学杂志

ABSTRACT

Objective To discuss the relationship between morphological characteristics of tumor microvasculature and blood supply type of primary hepatic cell carcinoma (HCC) through DSA. Methods From Jan. 1998 to Feb.2002, 32 cases, male 26,female 6,aged 28-76 (mean 50.56?10.52) years, underwent preoperative digital subtraction angiography (DSA) without therapeutic embolization in the 301 hospital and 307 hospital. The intervals between DSA and curative resections were 13-70 (mean 31.89?19.11) days. The diameters of the tumors were 2-23 (8.05?6.17) cm. The blood supply type of tumor, the tumor microvasculature density(MVD), type and diameter of the tumor microvessels, width of tumor trabecular were recorded for these cases. The outcomes were then statistically analysized. Results ① Blood supply of the tumor observed on DSA tended to be positively correlated with type of the tumor microvasculature. ②MVD of hypovascular tumors were lower than those in moderate and hypervascular tumors.③The ratio of diameters between tumor microvessel to the trabeculae of the tumor went higher with the increase of HCC blood supply on DSA. Conclusions ①The density, the configuration and the distribution of tumor microvasculature were not evenly distributed in HCC. ②The features of tumor microvasculature possessed distinctive characteristics in different stages of tumor growth, simultaneously with some definite developing rules. ③ Distinct differences in morphological characteristics of tumor microvasculature between different blood supply types of HCC.