Expression and significance of nuclear transcription factor in myocardium of rheumatic heart disease / 中华风湿病学杂志
Chinese Journal of Rheumatology
; (12)2003.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-574143
Responsible library:
WPRO
ABSTRACT
Objective To investigate the effects of nuclear transcription factor- kappa B (NF-!B) and activated protein- 1 (AP- l) on rheumatic myocardial fibrosis. Methods Thirty rheumatic myocardial specimens and 10 normal samples were examined by Masson′s staining, immunohistochemical staining and image analy- sis. Results Both NF- !B and AP- 1 were expressed in the nuclei of myocardium with rheumatic heart disease (RHD). The degree of positive staining in myocardiurn with RHD was significantly correlated with the cardial collagen volume (NF-!B r=0.8945, AP- 1 r=0.9011, P
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Rheumatology
Year:
2003
Document type:
Article