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The effect of Gengnianle Granule on hypothalamic-pituitary-ovarian axis in climacteric rats / 中成药
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-576242
Responsible library: WPRO
ABSTRACT

AIM:

To investigate the effect of Gengnianle Granule on hypothalamic-pituitary-ovarian(HPO) axis in climacteric rats.

METHODS:

12-15 months SD female rats were randomized into climacteric group and young control group was selected additionally.After being administrated for thirty days,the level of E_2、P、Te、FSH、LH in serum were examined by the radio-immunity method,the expression of GnRH in hypothalame,the expression of ER in hypothalame and pituitary appendage were examined by the immunohistochemical method.

RESULTS:

Compared with climacteric group,Gengnianle Granule could increase the level of E_2、P in serum(P

Full text: Available Database: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Chinese Traditional Patent Medicine Year: 1992 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Chinese Traditional Patent Medicine Year: 1992 Document type: Article
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