Protective Effect of Weishu Powder on Hepatic Injury Induced by Pentachloronitrobenzene / 广州中医药大学学报
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-579838
Responsible library:
WPRO
ABSTRACT
Objective To observe the protective effect of Weishu Powder(WP) on hepatic injury induced by pentachloronitrobenzene(PCNB).Methods SD rats were randomized into 4 groups normal group,model group,high-dosage WP group(in the dose of 2.50 g?kg-1 ?d-1) and low-dosage WP group(in the dose of 1.25 g?kg-1 ?d-1).Except the normal group,the other three groups received gastric gavage of PCNB 400 mg?kg-1 ?d-1 for 15 continuous days.After treatment,hepatic index was assayed,serum glutamic-oxalacetic transaminase(GOT) and alkaline phosphatase(ALP) levels and hepatic malondialdehyde(MDA) content were detected,and hepatic pathological examination was also carried out.Results Hepatic index,serum GOT and ALP levels,and hepatic MDA content were increased(P
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Journal of Guangzhou University of Traditional Chinese Medicine
Year:
2000
Document type:
Article