Quality Standard for Qingxin Anshen Soft Capsules / 中药新药与临床药理

ABSTRACT

Objective To establish the quality standard for Qingxin Anshen Soft Capsules. Methods Rhizoma Coptidis and Cortex Cinnamomi in Qingxin Anshen Soft Capsules were identified by TLC. Berberine hydrochloride and cinnamaldehyde were determined by HPLC. Results The characteristic identification by TLC was distinct and highly specific. The results of quantitative evaluation showed that berberine hydrochloride had the linear range of 0.6412 ?g～6.412 ?g(r=0.999 7,n=7),and the average recovery was 97.57 %(RSD=0.81,n=6);cinnamaldehyde had the linear range of 0.2148 ?g～2.148 ?g(r=0.999 8,n=7),and the average recovery was 97.70 %(RSD=0.88,n=6). Conclusion The method is reliable,accurate and specific. It can be used for the quality control of Qingxin Anshen Soft Capsules.