Mutational analysis of FUT1 and FUT2 genes in para-Bombay individuals / 中国输血杂志
Chinese Journal of Blood Transfusion
; (12)1988.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-584921
Responsible library:
WPRO
ABSTRACT
Objective To study the mutation of FUT1 and FUT2 genes in para-Bombay individual.Methods Direct DNA sequencing of FUT1 and FUT2 gene coding region were analyzed in two individuals with para-Bombay phenotype.Results One individual lost one of the three AG repeats located at nucleotides 547~552 of the FUT1 gene, whereas two of the three T repeats located at nucleotides 880~882 were deleted in the other.Conclusion Two frame-shift mutations of FUT1 gene are responsible for the H antigen deficiency
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Blood Transfusion
Year:
1988
Document type:
Article