Study of electromyography in patients with amyotrophic lateral sclerosis of different stages / 临床神经病学杂志

ABSTRACT

Objective To study the quantitative electromyography in patients with ALS of different stages and determine the sensitive parameters for early diagnosis.Methods Quantitative electromyography was performed in 371 muscles of 60 ALS patients and 275 control muscles. MUPs parameters, the presence of spontaneous activity and the recruitment order were measured. The electromyographic data were analyzed respectively and compared with the values obtained in the control group; Results There were obviously different electromyographic patterns in each stage. Six electrophysiological stages N_0-N_5 could be discerned from the early to the most advanced phase; Compared with those of the control group, the amplitude, area, duration, SI and polyphasia of MUPs all increased significantly in N_2 ( P