Study on correlation between expression of ref-1 and neuronal apoptosis after intracerebral hemorrhage in rats / 临床神经病学杂志
Journal of Clinical Neurology
; (6)1995.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-587203
Responsible library:
WPRO
ABSTRACT
Objective To investigate the correlation between the expression of redox factor-1 (Ref-1) and neuronal apoptosis around hematoma after experimental intracerebral hemorrhage (ICH) in rats.Methods ICH model of rat was induced using stereotactic infusion antilogous blood 50 ?l into the caudate nucleus. The male animals were randomly divided into sham operation group, normal control group and hemorrhage group. TUNEL and immunohistochemistry methods were used to detect apoptosis and the expression of Ref-1 in cerebral tissues at different time, respectively.Results The expression of Ref-1 was negatively correlated with neuronal apoptosis around hematoma after ICH (r=-0.745, P
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Clinical Neurology
Year:
1995
Document type:
Article