Effects of Levofloxacin on QTcd Interval in Elderly Patients Hospitalized with Acute Exacerbations of COPD / 中华医院感染学杂志
Chinese Journal of Nosocomiology
; (24)2006.
Article
in Zh
| WPRIM
| ID: wpr-589216
Responsible library:
WPRO
ABSTRACT
OBJECTIVE To study the effects of levofloxacin on QT correction dispersion(QTcd) interval in elderly patients hospitalized with acute exacerbations of COPD(AECOPD).METHODS Totally 124 patients received IV levofloxacin(500 mg qd) for 10-14 days.Evaluations included of 12-lead ECGs at baseline and blood examination before treatment,day 5 and after treatment.RESULTS QT correction(QTc) interval was no significant changes,but the QTcd interval was with significant prolongation.CONCLUSIONS IV levofloxacin could not cause QTc interval prolongation,but could make QTcd interval prolongation,which is a potential risk of arrhythmia in elderly patients with AECOPD.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Nosocomiology
Year:
2006
Document type:
Article