The roles of astrocytes in the pathogenesis of Parkinson's disease / 基础医学与临床

ABSTRACT

Parkinson's disease(PD) is a progressive neurodegenerative disorder harming mainly the elderly.Astrocyte may be involved in the pathogenesis of PD.However,it also plays a protective role in PD by releasing neurotrophic factors and glutathione to support the survival of dopaminergic neurons.Astrocyte may also release proinflammatory cytokines to promote the development of PD.