Bacteria and Drug Resistance Study of Respiratory Tract Infection for ICU Patients with Tracheostomy / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the respiratory tract infection rate,pathogenic organism and drug resistance for the patients with tracheotomy and endotracheal incubation in ICU,and to provide first-hand information for diseases prevention and clinical treatment.METHODS Fifty eight patients admitted in our hospital ICU from Dec 2006 to May 2007 were analyzed for their pathogenic organisms of lower respiratory tract infection,drug resistance,underlying diseases and age.RESULTS Pathogenic organisms from sputum culture for 58 patients with tracheotomy and endotracheal incubation were all positive.A total of 139 strains of pathogenic organisms have been found.Among them 106 were Gram-negative bacteria,accounted for 76.3%,and 26 were Gram-positive bacteria,accounted for 18.7% and 7 were fungi,accounted for 5%.From sputum culture of 29 patients Burkholderia cepacia was positive,which was the No.1 bacterial infection,accounted for 20.7% of total.Drug sensitive test for most Gram-negative bacteria showed resistance.CONCLUSIONS Bacteria infection of respiratory tract of the patients with mechanic ventilation in ICU is mostly Gram-negative.Clinical doctors should emphasize the inspection of pathogenic infection regularly and its drug resistance evaluation,to administer appropriate antibiotics.