Distribution and Drug Susceptibility of Bacteria Isolated from Patients with Biliary Tract Infection / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the distribution and drug susceptibility of microorganism isolated from patients with infection of biliary tract,and provide informations for clinical reasonable antibiotics selection. METHODS A total of 957 bile specimens of patients with infection of biliary tract were cultured and drug susceptibility test was performed. RESULTS From the 398 strains(66.67%) of microorganism were cultured.The main pathogenic bacteria were Escherichia coli(33.09%),Klebsiella pneumoniae(11.19%),Enterococcus faecalis(8.67%),Enterococcus faecium(5.78%) and Pseudomonas aeruginosa(4.69%).Meanwhile,the main pathogenic fungus was Candida albicans(7.22%).The susceptibility of Enterobacteriaceae to amikacin,imipenem and meropenem were 95.48%,100.00% and 100.00%,respectively.Susceptibility of Enterococcus to ampicillin and high concentration gentamicin were 73.61% and 84.72%,respectively. CONCLUSIONS E.coli,K.pneumoniae,E.faecalis and C.albicans are the main pathogens resulted in biliary tract infections.The strategy of amikacin combined with ampicillin may be recommended for empirical treatment in biliary tract infection.