Evaluation of a novel polymer-free sirolimus-eluting stent in a porcine model / 中国介入心脏病学杂志
Chinese Journal of Interventional Cardiology
; (4)1996.
Article
in Zh
| WPRIM
| ID: wpr-595715
Responsible library:
WPRO
ABSTRACT
Objective To evaluate the efficacy and safty of Polymer-free sirolimus eluting-stents(PFSES) in preventing restenosis in porcine coronary model.Methods Bare metal stents(BMS)(n=13),polymer-free bare metal stents(PFBMS)(n=13),polymeric sirolimus-eluting stents(PSES)(n=13) and PFSES(n=13) were implanted in left anterior descending coronary arteries(n=26) and left circumflex coronary(n=26) of 27 swines randomly.Coronary angiography was performed 28 days and 90 days after the procedure.Twelve animals were sacrificed for histomorphologic analysis after 90 days.Results The 28-day(n=24) and 90-day(n=12) outcome by quantitative coronary angiography(QCA) showed significant reduction in luminal loss(LL) in PFSES(LL:0.69?0.49 mm vs 1.27?0.36 mm,P=0.041;0.77?0.44 mm vs 1.33?0.29 mm,P
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Interventional Cardiology
Year:
1996
Document type:
Article