Combined examination of 64-slice spiral computed tomography and inflammatory cytokines in the detection of vulnerable plaque of acute coronary syndrome / 中国介入心脏病学杂志

ABSTRACT

Objective To evaluate the clinical value of 64-slice spiral computed tomography combined with hs-CRP and MMP-9 to detect the vulnerable plaque of acute coronary syndrome.Methods Seventy-two patients with coronary heart disease were included and among them,43 patients were diagnosed as ACS and the other 29 patients diagnosed as stable angina group(SAP).All patients underwent 64-slice spiral computed tomography coronary artery imaging and examination of plasma hs-CRP and MMP-9 concentration.All patients underwent selective coronary angiography.Another 25 cases who underwent coronary angiography were included in the control group.Results The incidence of soft plaque was higher in the ACS group than in the SAP group(24 cases vs 4 cases,P=0.001).Compared with the control group,levels of hs-CRP and MMP-9 in the ACS group and the SAP group were both significantly higher(all P