Research progress on derivatives of fucoidan / 国际生物医学工程杂志

ABSTRACT

Fucoidan is a kind of sulfated polysaccharide with a variety of biological activities.Chemical modification of polysaccharides can improve their bioactivities or make them produce new activities.In order to improve research of fucoidans and gain new polysaccharide drug with high bioactivity,this paper reviews preparative techniques and bioactivities of fucoidan derivatives,including low molecular weight fucoidan,desulfated fucoidan,oversulfated fucoidan,acetylated fucoidan,benzoylated fucoidan,phosphorylated fucoidan,aminated fucoidan and so on.