Amniotic cell culture and karyotype analysis of 1 016 pregnant women in second trimester / 国际检验医学杂志
International Journal of Laboratory Medicine
; (12): 1138-1139,1142, 2014.
Article
in Zh
| WPRIM
| ID: wpr-598972
Responsible library:
WPRO
ABSTRACT
Objective To investigate the application value of amniotic cell culture and karyotype analysis in prenatal diagnosis . Methods 1 016 pregnant women in second trimester were subject to amniocentesis under the guidance of B-type ultrasonic inspec-tion ,and the cell culture and karyotype analysis were performed on the amniotic fluid which had been drawn out .Results Among 1 016 pregnant women ,1 011(99 .5% ) succeeded in the first operation of amniocentesis and cell culture .The detection rate of fetal chromosomal abnormal karyotype was 10 .3% (105/1 016) ,in which 8 .3% (85/1 016) of structural abnormality and 2 .0%(20/1 016) of quantity abnormality .856 cases were received follow-up .Conclusion Amniotic fluid cell culture and karyotype analy-sis is a safe and reliable method for prenatal diagnosis .
Full text:
1
Database:
WPRIM
Type of study:
Guideline
Language:
Zh
Journal:
International Journal of Laboratory Medicine
Year:
2014
Document type:
Article