Neuroprotection and mechanisms of dexmedetomidine / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 1493-1495,1496, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-602693
Responsible library:
WPRO
ABSTRACT
Dexmedetomidine( DEX) is a pure potent, highly se-lective and highly specific agonist ofα2-adrenergic receptors with sedative, analgesic and sympatholytic properties. The sedative effect mimics natural sleep of“arousable” and“cooperative” se-dation without respiratory depression. Due to the above properties and advantages, DEX has received adequate attention in clinical practice and its spectrum of application is also expanding. In re-cent years, it is proved that DEX is neuroprotective not only in animal researches but also in clinical studies. The neuroprotec-tion of DEX and its related mechanism will be briefly reviewed in this paper.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2015
Document type:
Article