High-flow nasal cannula oxygen therapy and respiratory support in preterm infants / 国际儿科学杂志

ABSTRACT

High flow nasal cannulae(HFNC),a new mode of noninvasive respiratory support,by high-flow nasal cannula transports humidified,warmed and high flow maxed oxygen above the flow of 1 ~2 L/min. In the application of Neonatology,the higher oxygen flow and the smaller body type of newborn cause the stron-ger the expansion pressure by HFNC,and following the change of the amount of oxygen leaking along the con-duit.The effect of HFNC in improving respiratory parameters (such as neonatal tidal volume and respiratory function)was similar to nasal continuous positive airway pressure(NCPAP),but the effectiveness is limited to the flow less than 2L/min.A growing number of evidence suggests that HFNC as an alternative method for pre-term non-invasive alternative ventilation is available,but the effect and safety of applications in preterm still need further research.HFNC is not recommended popularized in preterm until more randomized trials to confirm.