Study on the Quality Standard for Tiaojing Zhuyun Granules / 中国药师
China Pharmacist
; (12): 1407-1408,1419, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-604371
Responsible library:
WPRO
ABSTRACT
Objective:
To establish the quality standard for Tiaojing Zhuyun granules .Methods:
A TLC method was used for the qualitative identification of main ingredients of Cornus officinalis and Angelica sinensis, and an HPLC method was used for the determi-nation of loganin in Tiaojing Zhuyun granule with SinoChrom ODS-BP (250 mm ×4.6 mm,5μm) as the analytical column .The mobile phase was composed of acetonitrile-0.1%phosphric acid solution (14∶86) at a flow rate of 1.0 ml· min-1 .The detection wavelength was set at 240 nm and the column temperature was 30℃.Results:
The corresponding spots in the granule were clear without any inter -ference from the negative control .The calibration curve of loganin was in good linearity over the range of 50 .40-1008 .00 ng ( r =0.999 9).The average recovery was 98.02%(RSD=2.51%,n=6).Conclusion:
The method is simple,feasible and reproducible, which can be used for the quality control of Tiaojing Zhuyun granules .
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Qualitative research
Language:
Chinese
Journal:
China Pharmacist
Year:
2016
Document type:
Article