Substance P, vasoactive intestinal peptide, gastrin, 5-hydroxytryptamine and gastrointestinal function / 国际儿科学杂志

ABSTRACT

Substance P,vasoactive intestinal peptide and gastrin belong to the gastrointestinal hormone;5-hydroxytryptamine(5-HT) is a neurotransmitter.Substance P and vasoactive intestinal peptide are widely present in the intestinal mucosa and play an important role in the intestinal motility and secretion.As the first gastro intestinal hormone whose molecular structure has been clarified,gastrin can promote gastrointestinal motility,for sports complex displacement damage caused by spontaneous and motilin,make the gastrointestinal movement in to postprandial fasting like movement.5-HT belongs to vasoactive amines,regulates the permeability of the blood vessel wall through 5-HT receptors.In this review,the origin,distribution and progress in gastrointestinal function of vasoactive intestinal peptide,gastrin and 5-hydroxytryptamine will be summarized.