Anti-leukemia effect and toxicity of arsenic trioxide: a review / 中国药理学与毒理学杂志
Chinese Journal of Pharmacology and Toxicology
; (6): 675-681, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-611108
Responsible library:
WPRO
ABSTRACT
Arsenic trioxide (As2O3) has been considered a poison,which is also known as an old drug and has recently been re-introduced as a new medicine.As2O3 shows potent effect on many types of cancers,especially on a specific types of leukemia-acute promyelocytic leukemia (APL).This poison drug As2O3 is effective against all stages of APL and has been approved by the Food and Drug Administration (FDA) of the United States for the treatment of APL.However,the clinical use of As2O3 has been limited by its toxicities,especially cardiotoxicity.This review focuses on the therapeutic effect on APL and the side effect during treatment.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pharmacology and Toxicology
Year:
2017
Document type:
Article