The epidemiological characteristics of perinatal birth defects in Xi'an from 2010 to 2015 / 西安交通大学学报(医学版)
Journal of Xi'an Jiaotong University(Medical Sciences)
; (6): 375-379, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-613469
Responsible library:
WPRO
ABSTRACT
Objective To investigate the dynamic epidemiological characteristics of perinatal birth defects in Xi'an so as to provide scientific evidence for the priority of future birth defect prevention.Methods We made a statistical description of the data of perinatal birth defects from 2010 to 2015 reported by all the maternity hospitals in Xi'an.Results The incidence of birth defects in Xi'an from 2010 to 2015 was 89.62/104 (87.60/104,91.74/ 104) and had an annual ascending tendency (x2-157.13,P<0.01).The top five main birth defects in a descending order were congenital heart disease (26.53/104),polydactyly (13.10/104),total cleft lip (11.42/104),neural tube defects (6.06 /104),and congenital hydrocephalus (5.08/104),accounting for 69.39% of the total number of birth defects.And the incidence of congenital heart diseases showed a year-by-year ascending trend (x2=837.65,P< 0.01).The incidence of birth defects was higher in urban areas than in rural areas (OR 1.108,95% CI1.056-1.162).The birth defects were more frequently seen in males than in females (OB=1.151,95% CI1.097-1.208).Mother's age <20 (OR=1.764,95% CI..1.532-2.032) and mother'sage≥35 (OR=1.283,95% CI1.179-1.395) also were risk factors for birth defects.Up to 72.54% of the defects were live births.There were 52.83% cases diagnosed by ultrasound and 46.24% ones by clinical examination.The prenatal diagnosis rate was 33.20%.Conclusion The incidence of perinatal birth defects in Xi'an from 2010 to 2015 showed an annual ascending trend.We should improve the prenatal diagnosis level of all monitored hospitals in order to reduce incidence of birth defects and increase the quality of population.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Risk factors
Language:
Chinese
Journal:
Journal of Xi'an Jiaotong University(Medical Sciences)
Year:
2017
Document type:
Article