Research progress of Akt in drug addiction mechanism / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 1046-1050, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-613673
Responsible library:
WPRO
ABSTRACT
Akt is the downstream target protein of phosphatidylinositol 3-kinase(PI3K),and PI3K/Akt signaling pathway is involved in cell proliferation,differentiation,apoptosis and metabolism.The activities of Akt in the central nervous system is also regulated by the neurotransmitter dopamine(DA),therefore Akt mediates multiple drug addiction process.This article reviews the structural characteristics and activity regulation of Akt,as well as the related research in drug addiction of this signal molecule.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2017
Document type:
Article