Role and mechanism of thrombin in white matter injury after intracerebral hemorrhage / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 449-453, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-617822
Responsible library:
WPRO
ABSTRACT
Intracerebral hemorrhage accounts for about 10%-30% of all stroke types.It is characterized by rapid onset, rapid progress, varied clinical symptoms, high morbidity and mortality, and poor prognosis.After the intracerebral hemorrhage, various inflammatory mediators result in white matter lesions and cognitive impairment.Thrombin acting on thrombin receptors at low concentration induces neuroprotection and at high concentration causes brain injury.This article reviews the role and mechanism of thrombin in white matter injury after intracerebral hemorrhage.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2017
Document type:
Article