Galectin-3 in differential diagnosis between benign and malignant thyroid follicular tumor / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery
; (6): 424-425, 2013.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-621988
Responsible library:
WPRO
ABSTRACT
Objective To analyze the expression of Galectin-3 in thyroid follicular tumors and its clinical significance in differential diagnosis between benign and malignant thyroid follicular tumor.Methods The expression of Galectin-3 in 120 cases of thyroid follicular carcinoma and 80 cases of thyroid follicular adenoma was detected by immunohistochemical technique.Results The expression rate of Galectin-3 in thyroid follicular carcinoma was significantly higher than that in follicular adenoma(84% vs 19%,P < 0.01).Strong positive expression of Galectin-3 was found in 40% cases of thyroid follicular carcinoma and no case of thyroid follicular adenoma.Conclusions The expression of Galectin-3 can be regarded as an important parameter for differential diagnosis between benign and malignant thyroid follicular tumor.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Endocrine Surgery
Year:
2013
Document type:
Article