Expression and Immunoreactivity of a Human Group A Rotavirus Vp4 / 中国病毒学
Virologica Sinica
; (4): 287-293, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-634675
Responsible library:
WPRO
ABSTRACT
Rotavirus capsid protein Vp4 plays an important role in the virus adhering and entering the cells. In this study, a Vp4 gene cloned from a rotavirus strain TB-Chen was highly expressed in E.coli BL21 (DE3). The results of the Western blot showed that the protein possesses specific immuno-reactivities and can be specifically recognized by guinea pig antibodies against rotavirus strain SA11 or Wa. Some Vp4 dimers were formed during renaturation. These data obtained from this study provide a strong basis for further study on the structure and function of the Vp4.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Virologica Sinica
Year:
2007
Document type:
Article