Expression and Significance of Ets- 1 in Chondrosarcoma and Osteochondroma of the Jaws / 上海第二医科大学学报
Journal of Shanghai Jiaotong University(Medical Science)
; (6): 550-552, 2000.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-635251
Responsible library:
WPRO
ABSTRACT
ObjectiveTo analyze the expression and significance of Ets- 1 (E26 transformation-specific) in chondrosareoma and osteochondroma of the jaws.MethodsEts- 1 expression was de-tected by immunohistochemistry in 20 cases of chondrosarcoma and 8 cases of osteochondroma of thejaws.Results12 of the 20 cases of chondrosarcoma (t50%) showed an Ets- 1 positive reastion. Thepositive rates of grade Ⅱ and grade Ⅲ were significantly higher than that of grade Ⅰ ( P < 0.05 ). Re-current cases showed a higher Ets - 1 positive rate than primary ones ( P < 0.05 ). Ets - 1 was presentin 12.5 % (1/8) osteochondroma. The positive rate was significantly different between chondrosarcomaand osteochondrorna ( P < 0.05 ).ConclusionThe results indicate that Ets- 1 is overexpressed inchondrosarcoma of the jaws and correlated with its pathological grade and recurrence.
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Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Shanghai Jiaotong University(Medical Science)
Year:
2000
Document type:
Article