Current approach to management of indirect traumatic optic neuropathy by glucocorticosteroid / 中华实验眼科杂志

ABSTRACT

Indirect traumatic optic neuropathy (ITON) is a primary cause of visual loss following head trauma.For the past decades,it has been a clinical dogma that mega-dose of methylprednisolone is beneficial in the treatment of ITON.However,there is still no convincing clinical evidence to support the effectiveness of these strategies up to now,so growing questions over whether glucocorticosteroid is beneficial for improving visual outcome in ITON patients are raised.Some recent studies even think that the effectiveness of glucocorticosteroid is not good enough for ITON or possible detrimental.Many researchers strongly advocate to carry out evidence-based multicenter randomized clinical trials (RCTs) to clarify this important issue.The current researches about application of glucocorticosteroid in the treatment of ITON are reviewed.