Cognitive Impairments in Clinically Stable Late-Life Depression : Relationship to Cardiovascular Risk : A Pilot Study
Journal of Korean Geriatric Psychiatry
; : 55-64, 2015.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-63680
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
The purpose of this study was to test the hypothesis that cardiovascular risk is associated with cognitive impairments in clinically stable late-life depression.METHODS:
A total of 59 clinically stable late-life depression patients over age 60 were enrolled in a cross-sectional study. Evaluation tools used in this study include Hamilton Rating Scale for Depression, Geriatric Depression Scale, State-Trait Anxiety Inventory, the Framingham general cardiovascular disease risk profile and the cognitive function battery designed for this study. Correlation analysis, analysis of variance and analysis of covariance were performed.RESULTS:
Patients with higher cardiovascular risk performed significantly poorer in the domains of executive function and short-term or long-term memory. In models adjusted for age, sex, education, 10% higher cardiovascular risk was associated with poorer executive function.CONCLUSION:
Our findings suggested that cardiovascular risk could be a significant factor associated with poor executive function in clinically stable late-life depression and the management which is necessary as a component of treatment planning. This pilot study provided good prospects for future studies to document this relationship on larger samples.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Anxiety
/
Cardiovascular Diseases
/
Pilot Projects
/
Cross-Sectional Studies
/
Depression
/
Education
/
Executive Function
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Memory, Long-Term
Type of study:
Etiology study
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Observational study
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Prevalence study
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Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Geriatric Psychiatry
Year:
2015
Document type:
Article