Extracorporeal cardiopulmonary resuscitation among patients with out-of-hospital cardiac arrest
Clinical and Experimental Emergency Medicine
; (4): 132-138, 2016.
Article
in En
| WPRIM
| ID: wpr-644719
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: Extracorporeal cardiopulmonary resuscitation (ECPR) may be considered as a rescue therapy for patients with refractory cardiac arrest. Identifying patients who might benefit from this potential life-saving procedure is crucial for implementation of ECPR. The objective of this study was to estimate the number of patients who fulfilled a hypothetical set of ECPR criteria and to evaluate the outcome of ECPR candidates treated with conventional cardiopulmonary resuscitation. METHODS: We performed an observational study using data from a prospective registry of consecutive adults (≥18 years) with non-traumatic out-of-hospital cardiac arrest in a tertiary hospital between January 2011 and December 2015. We developed a hypothetical set of ECPR criteria including age ≤75 years, witnessed cardiac arrest, no-flow time ≤5 minutes, low-flow time ≤30 minutes, refractory arrest at emergency department >10 minutes, and no exclusion criteria. The primary endpoint was the proportion of good neurologic outcome of ECPR-eligible patients. RESULTS: Of 568 out-of-hospital cardiac arrest cases, 60 cases (10.6%) fulfilled our ECPR criteria. ECPR was performed for 10 of 60 ECPR-eligible patients (16.7%). Three of the 10 patients with ECPR (30.0%), but only 2 of the other 50 patients without ECPR (4.0%) had a good neurologic outcome at 1 month. CONCLUSION: ECPR implementation might be a rescue option for increasing the probability of survival in potentially hopeless but ECPR-eligible patients.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Extracorporeal Membrane Oxygenation
/
Prospective Studies
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Cardiopulmonary Resuscitation
/
Emergency Service, Hospital
/
Out-of-Hospital Cardiac Arrest
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Tertiary Care Centers
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Observational Study
/
Heart Arrest
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Adult
/
Humans
Language:
En
Journal:
Clinical and Experimental Emergency Medicine
Year:
2016
Document type:
Article