Re-evaluation of Association between Thrombotic Diasthesis and Legg-Calve-Perthes Disease / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
; : 189-194, 1999.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-650650
Responsible library:
WPRO
ABSTRACT
Legg-Calve-Perthes disease (LCP) has been reported to be associated with hypofibrinolysis and a deficiency in coagulation. The goal of this prospective study was to confirm or refute these findings and to establish a guide for a screening test. The coagulation systems of twenty-three patients with Legg-Calve-Perthes disease were evaluated by means of the tests which included prothrombin time, activated partial thromboplastin time, antithrombin-III (AT-III), protein C, protein S, lipoprotein(a), and anticardiolipin antibody (ACA). Study subjects were 21 males and 2 females. Mean age was 8.7 years. No abnormal results were found for Antithrombin-III and Protein S, but 2 patients had low Protein C level. Two of 23 patients had Lipoprotein(a) values greater than 30 mg/dl. Another two patients had positive finding for Anticardiolipin antibody. There were no statistical differences in all parameters between Catterall group stage in the patients with Legg-Calve-Perthes disease. We were unable to establish an association between thrombotic tendency and Legg-Calve-Perthes disease based on this prospective study. So, routine screening of patients with Legg-Calve-Perthes disease for abnormalities of antithrombotic factors would be not warranted.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Partial Thromboplastin Time
/
Prothrombin Time
/
Protein C
/
Mass Screening
/
Prospective Studies
/
Protein S
/
Lipoprotein(a)
/
Antibodies, Anticardiolipin
/
Legg-Calve-Perthes Disease
Type of study:
Observational study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Journal of the Korean Orthopaedic Association
Year:
1999
Document type:
Article